About the Disease

Hereditary angioedema (HAE) is a hereditary disorder affecting the immune system that causes recurrent episodes of severe swelling, most commonly in the limbs, face, intestines and airway. The condition is a result of low levels or improper functioning of a protein called C1 inhibitor. While minor trauma or stress could trigger an attack, swelling often occurs without a known trigger. Swelling in the intestines cause severe abdominal pain, nausea and vomiting, while swelling in the airway can restrict breathing and result in a life-threatening obstruction. Untreated, attacks can occur much more frequently, with some reported cases of daily incidents.

Three different clinical types of Hereditary angioedema have been identified.

Type I Hereditary Angioedema - HAE-I

Characterized by low levels of C1-INH

Type II Hereditary Angioedema  - HAE-II

Characterized by poorly functioning C1-INH

Type III Hereditary Angioedema  - HAE-III

Characterized by normal functioning C1-INH

About the Patient Care

Our dedicated Care Team will work with the physician's office and insurance on a patient's behalf so that our patients have more time to focus on their treatment and quality of life. We are here to listen, provide

counseling on treatment, including side-effect management, and assist with sourcing third-party financial assistance.

As part of treatment, we provide:

Dedicated Care Team

We provide prescribers and patients with a dedicated care team for each of our disease state programs. This includes a primary pharmacy contact, clinical education, side-effects management, scheduled refill calls, and a direct phone, fax and email address.

In-Home Patient- and Family-Centric Care

We administer a nationwide nursing network, allowing patients to pursue in-home treatment or receive training on self-administrated drugs. Our nurses are ideally positioned to establish a partnership with patients and their families in order to provide clinical education and coaching that strengthen the patient's capacity to achieve therapy goals.

Shipping and Coordination of Care

We provide free overnight delivery of medications and necessary medical supplies and manage the coordination of care between prescribers, sites of care, nurses and patients to ensure dispenses and drug delivery align with the date and location of service.

Financial Assistance

We successfully identify and assist enrolling patients into any and all manufacturer co-pay and foundation support programs in order to minimize a potential financial burden to patients given the high-cost of specialty medications.

24/7/365 Access to a Pharmacist

We provide prescribers and patients access to a pharmacist 24/7/365 to ensure patients are always cared for.


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Supported Treatments

Berinert (C1 esterase inhibitor)

Brand Name | Berinert

Manufacturer | CSL Berhing

Route of Administration | Intravenous (IV) injection

Approved Indication | Treatment of acute abdominal, facial, or laryngeal HAE attacks in adult and pediatric patients

Self-Administration | Yes, after training

Product Website | www.berinert.com

Cinryze (C1 esterase inhibitor)

Firazyr (icatibant)

Haegarda (C1 esterase inhibitor)

Kalbitor (ecallantide)

Ruconest (C1 esterase inhibitor)

Takhzyro (lanadelumab-flyo)

Partnering with Prescribers

Licensed prescribers can submit a completed enrollment form directly to our Admission team. We will begin the process and communicate with your office every step of the way.

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